The Tangerines started brightly but found themselves a goal down after just 12 minutes when Theo Walcott finished off a slick Arsenal passing move.
Gary Taylor-Fletcher then headed wide Pool's best opportunity to draw level climbing high at the back post only to head Stephen Crainey's cross wide of Manuel Almunia's goal.
Shortly after Evatt was off and Ollie's men were two down after only 32 minutes.
There was time for Walcott to grab his second and Arsenal's third before half time when Chamakh played him in after 39 minutes.
At half time the game had gone and the only question remaining was; how many can Arsenal score?
Abou Diaby added a fourth just three minutes after the restart and Theo Walcott later superbly added his hat-trick goal, passing the ball into the bottom right corner of Matt Gilks' goal after 58 minutes.
Despite being 5-0 down with over half an hour still to play, Blackpool's fans could not be silenced. The Tangerine Army were a credit to their Football Club throughout the game and did not stop cheering on their team at any point throughout the 90 minutes.
Arsene Wenger decided to give Pool a break when he replaced hat-trick hero Walcott and Diaby, only to give world cup finalists Cesc Fabregas and Robin Van Persie a run out for the final thirty minutes.
Blackpool defended resolutely for the remainder of the contest and only had their goal breached one more time by Moroccan International Chamakh who himself should have had at least a hat-trick of goals.
After the game Ian Holloway and Arsene Wenger both paid tribute to Blackpool's fans who supported their team throughout and were making more noise than the home supporters at the final whistle.
The players and coaching staff should not be too disheartened by results like this away from home against one of the league's top gun's. Ultimately results against teams around the bottom half of the table will decide Pool's fate this season.
Despite defeat, Blackpool still find themselves in the top half of the Premier League table.
So don't stop believing, don't lose heart, enjoy the roller-coaster ride this season and keep up the super support.
FT: Arsenal 6 - 0 Blackpool
Walcott 12, 39, 58
Arshavin 32 (pen)
Arsenal: Almunia, Sagna, Song, Vermaelen, Clichy, Diaby (>62), Wilshere, Walcott (>62), Rosicky, Arshavin (>66), Chamakh. Subs: Fabianski, Fabregas (<62), Van Persie (<62), Vela (<66), Djourou, Eboue, Gibbs
Blackpool: Gilks, Baptiste, Evatt, Cathcart, Crainey, Sylvestre (>37), Vaughan, Adam, Grandin, Harewood (>57), Taylor-Fletcher (>57). Subs: Halstead, Eardley, Ormerod (<57), Basham, Edwards, Ishmel (<57), Keinan (<37)
Venue: Emirates Stadium
Referee: Michael Jones